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They enhance the effect of EGF on DNA synthesis and prevent transglutaminase 2 (TG2)-mediated transamidation of the EGFR in hepatocytes by binding to α1-adrenergic receptors (α1-ADR) 182,589,590 Additionally, other research suggests that catecholamines also support the proliferation of cholangiocytes and LPCs

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Cell Mol Life Sci5910241041